Prg4-CreERT2-2A-EGFP
모델명
C57BL/6Smoc-Prg4em(Kozak-CreERT2-2A-EGFP-WPRE-pA)1Smoc
카탈로그
NM-KI-225074
모델 상태
Repository Live
유전자 요약
Official Symbol
Prg4
모델 설명
검증 데이터
Fig 1. Cre-mediated recombination in bone of Prg4CreERT2-EGFP/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) and GFP (green) in various tissues of Prg4CreERT2-EGFP/+; Rosa26tdTomato/+ mice. Expression tissues include: liver, bone, spleen, muscle, hair follicle. A few cells expressed in heart, salivary gland, adrenal gland, small intestine, testis. Tissues that unexpressed include brain, spinal cord, retina, lung, stomach, brown fat, kidney, colon, pancreas, thymus, pituitary. (37-day old, male)
TdTomato labeling was observed in tissue sections of Prg4CreERT2-EGFP/+;Rosa26tdTomato/+ untreated treated groups, indicating spontaneous Cre activity in the absence of tamoxifen.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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