Drd1-2A-CreERT2

모델명

C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc

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NM-KI-18016

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Drd1

모델 설명

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
신청분야:Cre recombinase tool

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验证数据-Drd1a-CreERT2-图片1.png

Figure 1:CreERT2-mediated recombination in brain of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in brain of Drd1a CreERT2; R26 tdTomato mice.

验证数据-Drd1a-CreERT2-图片2.png

Figure 2:CreERT2-mediated recombination in CPU(corpus striatum) of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in CPU of Drd1a CreERT2; R26 tdTomato mice.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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