Lyz2-2A-CreERT2
모델명
C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
카탈로그
NM-KI-18018
모델 상태
Repository Live
유전자 요약
Official Symbol
Lyz2
모델 설명
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
신청분야：Cre recombinase tool
*Literature published using this strain should indicate: Lyz2-2A-CreERT2 mice (Cat. NO. NM-KI-18018) were purchased from Shanghai Model Organisms Center, Inc..
검증 데이터
Fig1 Evaluation of CreERT2 recombination in Lyz2 Cre+/-;R26 tdT+/- mice.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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