Scgb3a2-IRES-Cre

모델명

C57BL/6Smoc-Scgb3a2em1(IRES-Cre-polyA)Smoc

카탈로그

NM-KI-210127

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Scgb3a2

Synonyms

Pnsp1; UGRP1; LuLeu1; Utgrp1

NCBI ID

117158

MGI ID

2153470

Ensembl ID

ENSMUSG00000038791

Pubmed

Scgb3a2

Human Ortholog

SCGB3A2

모델 설명

IRES-Cre-polyA expression cassette was knocked into the Scgb3a2 gene.
신청분야：Secretoglobin (SCGB) 3A2 is a member of the SCGB gene superfamily of cytokine-like secretory proteins of small molecular weight. SCGB proteins mainly expressed in airway epithelial cells.

검증 데이터

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Fig. 1  Cre-mediated recombination in the lung of Scgb3a2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the epithelial cells of Scgb3a2Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Scgb3a2Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the airway epithelium cells of an adult female mouse. TdTomato can also be detected in individual cells of salivary glands, ovary, spleen and spinal cord. TdTomato can not be detected in the pituitary, oviduct, liver and eyes. (For more detailed information please contact our technical advisor.)

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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