Tg-2A-CreERT2

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C57BL/6Smoc-Tgem1(2A-CreERT2-WPRE-polyA)Smoc

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NM-KI-215040

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Sperm cryopreservation

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Col1a2

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2A-CreERT2-WPRE-polyA expression cassette was knocked into the Tg gene.


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Fig1. Cre mediated recombination in thyroid of TgCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of TgCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: thyroid gland and salivary gland. A few cells expressed in lung, liver, adrenal gland, kidney, colon, small intestine, spleen, ovary, thymus and pituitary gland. Tissues that unexpressed include brain, spinal cord, retina, heart, stomach, brown fat, pancreas, muscle, epidermis.Thyroid is expressed before induction.(4-weeks old, male) (For more detailed information please contact our technical advisor.) 


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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