Mnx1-IRES-Cre

모델명

C57BL/6Smoc-Mnx1em1(IRES-Cre-WPRE-polyA)Smoc

카탈로그

NM-KI-200010

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Mnx1

Synonyms

HB9; MNR2; Hlxb9

NCBI ID

15285

MGI ID

109160

Ensembl ID

ENSMUSG00000001566

Pubmed

Mnx1

Human Ortholog

MNX1

모델 설명

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Mnx1 gene stop codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Mnx1. These mice may be useful for studying spinal muscular atrophy (SMA).
신청분야：Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the spinal cord of Mnx1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the spinal cord of Mnx1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Mnx1Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the brain, kidney, intestine, colon, eyes, ovary, salivary gland, stomach, liver, skin, heart, lung, pituitary gland, muscle, spleen, brown fat and thymus. (For more detailed information please contact our technical advisor.)


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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