Slc32a1-IRES-Cre

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C57BL/6Smoc-Slc32a1em1(IRES-iCre)Smoc

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NM-KI-200081

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Slc32a1

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A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.
신청분야:Cre recombinase tool; Slc32a1 is a member of the GABA Vesicular Transporter Family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying GABaergic neurons function.

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Fig. 1 Cre-mediated recombination in the brain of Slc32a1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex, hippocampus, hypothalamus and cerebellum of Slc32a1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Slc32a1Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the cortex, hippocampus, hypothalamus, cerebellum, retinal ganglion cell layer, retinal outer plexiform layer and inner nuclear layer. TdTomato can also be detected in individual cells of the sailvary gland, kidney, pancreas, large intestine, spleen, thymus, testis and epididymis. Tdtomato expression can not be observed in the heart, lung, liver, small intestine and skin. (For more detailed information please contact our technical advisor.)



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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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