Slc17a7-IRES-Cre

모델명

C57BL/6Smoc-Slc17a7em1(IRES2-iCre)Smoc

카탈로그

NM-KI-200086

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Slc17a7

Synonyms

Vglut1; AI851913; 2900052E22Rik

NCBI ID

72961

MGI ID

1920211

Ensembl ID

ENSMUSG00000070570

Pubmed

Slc17a7

Human Ortholog

SLC17A7

모델 설명

A IRES2-iCre expression cassette was knocked into the Slc17a7 gene stop codon site.
신청분야：Cre recombinase tool; Slc17a7(Sodium dependent Inorganic Phosphate cotransporter) is also known as Vglut1(Glutamate transporter). When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Slc17a7. This strain may be useful for studying glutamatergic synaptic vesicle trafficking and vesicle-bound, sodium-dependent phosphate transportation.

검증 데이터

image.png

Fig. 1 Cre-mediated recombination in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) is widely expressed in the brain of Slc17a7Cre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of Slc17a7Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the brain, pituitary gland, eyes, heart, skin and colon. TdTomato can also be detected in individual cells of the lung, liver, stomach, submandibular gland, brown fat, muscle, spleen, thymus, small intestine, pancreas, kidney and epididymis. (For more detailed information please contact our technical advisor.)


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회