Vip-IRES-Cre

모델명

C57BL/6Smoc-Vipem1(IRES-iCre-SV40-pA)Smoc

카탈로그

NM-KI-200100

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Vip

Synonyms

-

NCBI ID

22353

MGI ID

98933

Ensembl ID

ENSMUSG00000019772

Pubmed

Vip

Human Ortholog

VIP

모델 설명

A IRES-iCre expression cassette was knocked into the Vip gene stop codon site. Vip encodes vasoactive intestinal polypeptide. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in cells expressing. This strain is useful for studying bronchiectasis, immunomodulatory and anti-inflammatory.
신청분야：Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the brain of VipCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex of VipCre/+; Rosa26tdTomato/+ mouse. 

vip.png

Fig. 2 Detection of tdTomato(red) in various tissues of VipCre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the cortex, olfactory bulb, colon, epididymis, kidney, muscle, spleen, stomach, thymus, brown fat, intestine, heart, retina, liver, lung, pancreas, testis, salivary gland and skin. (For more detailed information please contact our technical advisor.)


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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