Nkx2-1-CreERT2
모델명
C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
카탈로그
NM-KI-200123
모델 상태
Sperm cryopreservation
유전자 요약
Official Symbol
Nkx2-1
모델 설명
검증 데이터
Fig. 1 Detection of tdTomato (red) in the pulmonary epithelial cells of Nkx2-1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. CreERT2-mediated recombination in some of the bronchial and alveolar epithelial cells of Nkx2-1CreERT2/+; Rosa26tdTomato/+ mouse can be induced by tamoxifen.
Fig. 2 Detection of tdTomato (red) in various tissues of Nkx2-1CreERT2/+; Rosa26tdTomato/+ mice after tamoxifen treatment. CreERT2-mediated recombination in the lung can be induced by tamoxifen. And tdTomato expression can not be observed in the pituitary gland, retina, heart, liver, stomach, colon, intestine, kidney, pancreas, etc.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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