Trpv1-IRES-Cre

모델명

C57BL/6Smoc-Trpv1em1(Myc-IRES-Cre)Smoc

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NM-KI-200139

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Trpv1

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A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.
신청분야:Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the brain of Trpv1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the dentate gyrus of Trpv1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Trpv1Cre/+; Rosa26tdTomato/+ mice. Tdtomato is expressed in the brown fat, pancreas, kidney, retina, brain, pituitary gland, heart, lung, liver, stomach, salivary gland and skin. Tdtomato expression can also be observed in individual cells of the testis, epididymis, muscle, spleen, thymus, intestine and colon. (For more detailed information please contact our technical advisor.)



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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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