Tmem119-2A-CreERT2

모델명

C57BL/6Smoc-Tmem119em2(P2A-CreERT2)Smoc

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NM-KI-200234

모델 상태

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유전자 요약

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Tmem119

모델 설명

A P2A-CreERT2 expression cassette was knocked into the Tmem119 gene stop codon site.
신청분야:Cre tool mice

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图片5.png图片6.png图片7.pngFig1. Tmem119-CreERT2 mice effectively recombine a conditional allele in microglia.

A-B. Confocal micrograph showing tdTomato expression in IBA-positive microglia upon tamoxifen administration , Absence of tdTomato expression in untreated animals. C-D, Representative immunostaining for  astrocytes (C, GFAP, green), and neurons (D, NeuN, green) in tdTomato-expressing microglia of Tmem119-CreERT2+/−; Rosa26 tdTomato+/− mice. 

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당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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