Dppa3-IRES-Cre

모델명

C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc

카탈로그

NM-KI-00040

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Dppa3

Synonyms

PCG7; PGC7; Stella; 2410075G02Rik

NCBI ID

73708

MGI ID

1920958

Ensembl ID

ENSMUSG00000046323

Pubmed

Dppa3

Human Ortholog

DPPA3

모델 설명

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.
신청분야：Dppa3 (also known as Pgc7 or Stella) plays an important role in early embryonic development during the cleavage stage as a maternal effect gene.

검증 데이터

image.png

Fig. 1 Detection of Zsgreen(green) in various tissues of Dppa3Cre/+; Rosa26Zsgreen/+mice. Zsgreen expression can be detected in the brain, heart, lung, submandibular gland, salivary gland, stomach, kidney, pancreas, testis, epididymis, colon and spleen of Dppa3Cre/+; Rosa26Zsgreen/+mouse. (For more detailed information please contact our technical advisor.)

image.png

Fig. 2 Cre-mediated recombination in the E14.5 Dppa3Cre/+; Rosa26tdTomato/+ mouse embryos. 

간행물

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
References：Nature Communications

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회