Epcam-2A-CreERT2

모델명

C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc

카탈로그

NM-KI-00084

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Epcam

Synonyms

EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1

NCBI ID

17075

MGI ID

106653

Ensembl ID

ENSMUSG00000045394

Pubmed

Epcam

Human Ortholog

EPCAM

모델 설명

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

검증 데이터

kidney.png

Fig1 CreERT2-mediated recombination in kidney cells of Epcam CreERT2+/-;R26 tdTomato+/- mice. Detection of tdTomato epifluorescence (red) and co-immunostaining for Epcam (green) in kidney cells of Epcam CreERT2+/- ;R26 tdTomato+/- mice.

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Fig2 CreERT2-mediated recombination in liver of Epcam-CreERT2+/-;R26 tdTomato+/- mice.

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Fig3 CreERT2-mediated recombination in small Intestines of Epcam-CreERT2+/-;R26 tdTomato+/- mice.

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Fig4 CreERT2-mediated recombination in large Intestines of Epcam-CreERT2+/-;R26 tdTomato+/- mice.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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