hFcRn(SD)

모델명

SD-Fcgrtem1(hFCGRT)Smoc

카탈로그

NR-HU-200002

모델 상태

Repository Live

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유전자 요약

모델 설명

The endogenous rat Fcgrt gene was replaced by human FCGRT gene.
신청분야:cancer research,Immunotherapy,drug screening

검증 데이터

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Fig1. Expression characterization of hFCRN in hFCRN knockin rat by Western blot. 

Abbr. HO, homozygous; WT, wild type.

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Fig2. PK study of Keytruda in hFCRN rat.

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Fig3. PK study of Cyramza in hFCRN rat.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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