B2m-KO

모델명

C57BL/6Smoc-B2mem3Smoc

카탈로그

NM-KO-18021

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
B2M

모델 설명

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.
신청분야:immune system

검증 데이터

b2m流式.png

Fig1 . There are few CD8+ cytotoxic T-cells and increase in CD4+ T-cells in B2M knockout mice. Immune responses involving CD8+T-cells are severely deficient providing a model to assess the role of CD8+ cells and class I MHC in various experimental systems. 



당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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