HBV-Tg

모델명

B6.Cg-Tg(HBV)Smoc

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NM-TG-00003

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Full-length HBV genome (adrsubtype,C genotype) was used to establish the transgenic mice. HBsAg was positive in transgenic mice serum; no serum HBeAg anti-HBs, anti-HBe, or antiHBc was detected. No anti-HBs or anti-HBe was detected in the polyethylene gly.
신청분야:HBV

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Fig1. Immuno-histochemical staining of HBsAg in the liver and kidney sections of #59 transgenic mice. Sections of liver (A) or kidney (B) tissues from #59 transgenic mice were stained for HBsAg.

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Fig2.  Immuno-histochemical staining of HBcAg in the liver and kidney sections of #59 transgenic mice.

Sections of liver (A) or kidney (B) tissues from #59 transgenic mice were stained for HBcAg.

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Tab1. Eight Selected Genes From the Kidney of #59 Mice Assayed by Microarray and Real-Time PCR

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Fig3.  Dot blot immunoassay of complement C3 component in mouse serum and kidney tissue extract.



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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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