Raji-Luc

PDF 받기

Strain Information

검증 데이터

The Raji-Luc cell line is a Raji wild-type cell line with stable and high expression of Luciferase.  Luciferase activity was showed a steady increase in xenograft mouse models. This Raji-Luc cell line is available for in vivo imaging and assessment of novel therapeutic modalities.

image.png

Figure 1. Morphology of Raji-Luc cell line.

image.png

Figure 2. Luciferase activity assay of Raji-Luc cell lines.

image.png

Figure 3. Average growth curves of Raji-Luc tumors in xenograft mouse models. (n=5) 

M-NSG (A) and hIL-15 M-NSG (B) mice were subcutaneously injected with Raji-Luc cells.

image.png

Figure 4.  In vivo luciferase activity curves of Raji-Luc xenograft mouse models.  (n=5)

M-NSG mice (A, B) and hIL-15 M-NSG mice (C) were inoculated with Raji-Luc cells through tail vein injection.

image.png

Figure 5.  Survival curves of Raji-Luc xenograft mouse models. (n=5)

M-NSG mice (A) were subcutaneously (s.c.) injected with Raji-Luc cells. While M-NSG mice (B) and hIL-15 M-NSG mice(C) were inoculated with Raji-Luc cells through tail vein injection.

image.png

Figure 6. In vivo bioluminescence imaging of Raji-Luc xenograft mice.

M-NSG mice were subcutaneously (s.c.) injected with Raji-Luc cells.

image.png

Figure 7. In vivo Raji-Luc tumor cell signal was inhibited by targeted drug in M-NSG mice. (n=5)


Related Strain(s)

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회