Tff1-2A-CreERT2

모델명

C57BL/6Smoc-Tff1em1(2A-CreERT2-polyA)Smoc

카탈로그

NM-KI-200244

모델 상태

Repository Live

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유전자 요약

Gene Symbol
Tff1

모델 설명

将2A-CreERT2-polyA共表达结构插入到小鼠Tff1基因终止密码子处。
신청분야:Cre工具鼠

검증 데이터

Tff1-CreERT2-1 - 副本.png

图 1 Tff1CreERT2/+; Rosa26tdTomato/+ 小鼠胃粘膜上皮细胞中tdTomato的表达情况。

经Tamoxifen诱导后,Tff1CreERT2/+; Rosa26tdTomato/+ 双转基因鼠,可在小鼠胃粘膜上皮细胞中表达tdTomato。证明Tff1-(CreERT2)小鼠可以成为实现Tff1阳性细胞特异性敲除或表达的工具鼠。

Tff1-CreERT2-2 - 副本.png

图 2: Tamoxifen诱导后,Tff1CreERT2/+; Rosa26tdTomato/+ 小鼠各组织中tdTomato的表达情况。


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