hSORT1

모델명

C57BL/6JSmo-Sort1tm1(hSORT1)Smoc

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NM-HU-225035

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol
Sort1

모델 설명

The endogenous mouse Sort1 gene was replaced by human SORT1 gene.

검증 데이터

image.png

Fig1. Detection of SORT1 expression in lung and colon by RT-PCR. 

Wild type: only one band at 205 bp with primers F1/R1(mSort1);

Heterozygous: one band at 205 bp with primers F1/R1(mSort1) and one band at 193 bp with primers F2/R2 (hSORT1). 

Abbr.. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human SORT1 expression in lung in hSORT1 knockin mice by WB. 

Abbr. HO, homozygous; WT, wild type.

Note: The anti-human SORT1 antibody cross-reacted with mouse SORT1 and humanized SORT1.


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