hAPOE3

모델명

C57BL/6JSmo-Apoetm3(hAPOE3)Smoc

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NM-HU-190003

모델 상태

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유전자 요약

Gene Symbol
Apoe

모델 설명

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.
신청분야:Cardiovascular disease

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Validation data

Apoe3-2.png

Fig1. Genotyping of WT 、KO &  Humanized mice by PCR.

Primer P1/2 Wild type = 342 bp

Primer P3/4 mutant = 332 bp

M:100bp Plus DNA ladder.

image.png

Fig2. Western blot analysis of  APOE3 protein from  WT、KO & Humanized mice. 


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