hVSIG4
모델명
C57BL/6JSmo-Vsig4tm1(hVSIG4)/Smoc
카탈로그
NM-HU-210004
모델 상태
Embryo cryopreservation
유전자 요약
Gene Symbol
Vsig4
모델 설명
검증 데이터
Fig1. Analysis of human VSIG4 expression on the peritoneal exudate macrophages by FACS.
The homozygous KI mouse expresses human VSIG4 on the peritoneal exudate macrophages.
Fig.2 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.
Body weight were measured twice a week of hVSIG4 mice (n=4 , 3 male and 1 female). (A) Body weight. (B) Body weight change.
Fig.3 In vivo efficacy assessment of anti-hVSIG4 in HO hVSIG4 mice bearing MC38 syngeneic tumor.
Tumor volume were measured twice a week of hVSIG4 mice. MC38 (1×106) were inoculated subcutaneously into hVSIG4 mice (6-8-week-old, n=4, 3 male and 1 female). (A) Tumor volume. (B) Relative tumor volume.
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