hCLEC6A

모델명

C57BL/6JSmo-Clec4ntm(hCLEC6A)Smoc

카탈로그

NM-HU-220516

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol
Clec4n

모델 설명

The endogenous mouse Clec4n gene was replaced by human CLEC6A gene.

검증 데이터

image.png

Fig.1 Detection of CLEC6A expression in spleen and thymus by RT-PCR. 

Wild type: only one band at 189 bp with primers F1/R1(mClec4n);

Homozygous: only one band at 194 bp with primers F2/R2(hCLEC6A).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human and mouse CLEC6A expression on MHC-II+ BMDCs by FACS. 

The BMDCs were activated by GM-CSF and mIL-4 before detection.  (male, HO: 10wks, WT: 8-10wks)


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