hGPR146

모델명

C57BL/6JSmo-Gpr146tm1(hGPR146)Smoc

카탈로그

NM-HU-233622

모델 상태

Repository Live

PDF 받기

유전자 요약

Gene Symbol
Gpr146

모델 설명

The endogenous mouse Gpr146 gene was replaced by human GPR146 gene.

검증 데이터

image.png

Fig.1 Detection of GPR146 expression in liver, white and brown adipose tissue, lung, heart, and kidney by RT-PCR. 

Wild type: only one band at 339 bp with primers F1/R1(mGpr146);

Homozygous: only one band at 234 bp with primers F2/R2(hGPR146).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GPR146 expression in hGPR146 mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; BAT, brown adipose tissue; PC, positive control, HCT116 cells.

Note. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

조회

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회