Fgd5-P2A-ZsGreen-T2A-CreERT2

모델명

C57BL/6Smoc-Fgd5em1(P2A-ZsGreen-T2A-CreERT2)Smoc

카탈로그

NM-KI-232113

모델 상태

Sperm cryopreservation

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유전자 요약

Gene Symbol
Fgd5

모델 설명

The P2A-ZsGreen-T2A-CreERT2 expression cassette was knocked into the Fgd5 gene stop codon site.

검증 데이터

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Fig1. Cre mediated recombination in spleen of Fgd5ZsGreen-CreERT2/+; Rosa26tdTomato/+ mouse.

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Fig2. Detection of zsGreen(green) and tdTomato(red) in various tissues of Fgd5ZsGreen-CreERT2/+; Rosa26tdTomato/+ mouse. 

The tissues expressing tdTomato and zsGreen include: spleen.

The tissues expressing tdTomato include: brain, spinal cord, eyes, heart, lungs, liver, stomach, salivary glands, brown adipose tissue, adrenal glands, kidneys, large intestine, small intestine, spleen, pancreas, reproductive organs, muscles, skin, thymus, and pituitary gland.

In the control group, tdTomato shows very minimal leaky expression in: muscles and adrenal glands.

The tissues expressing zsGreen include: spleen.

In the control group, zsGreen shows very minimal leaky expression in: adrenal glands. (6-weeks old, male) (For more detailed information please contact our technical advisor.) 


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