hTIGIT/hPVR

모델명

C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc

카탈로그

NM-HU-2000091

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol

Synonyms

Vstm3，PVS， mE4， HVED， Taa1， CD155， Tage4， necl-5， D7Ertd458e， 3830421F03Rik

NCBI ID

100043314，52118

MGI ID

3642260，107741

Ensembl ID

ENSMUSG00000071552，ENSMUSG00000040511

Pubmed

Human Ortholog

TIGIT，PVR

모델 설명

These mice are obtained through breeding of two single gene humanized mice.
신청분야：Immunotherapy,cancer research,drug screening

검증 데이터

TIGIT.png

Fig.1 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mTIGIT+ cells were detectable in wild type (WT) C57BL/6, while hTIGIT+ cells were detectable in the homozygous TIGIT&PVR mice. 

PVR.png

Fig.2 Splenocytes from homozygous TIGIT&PVR mice were analyzed by flow cytometry after activation. mPVR+ cells were detectable in wild type (WT) C57BL/6, while hPVR + cells were detectable in the homozygous TIGIT&PVR mice.

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