hPVRIG

모델명

C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc

카탈로그

NM-HU-210008

모델 상태

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유전자 요약

Gene Symbol
Pvrig

Synonyms

Gm36869

NCBI ID

102640920

MGI ID

5596028

Ensembl ID

ENSMUSG00000109713

Pubmed

Pvrig

Human Ortholog

PVRIG

모델 설명

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.
신청분야：drug screening

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Fig1. Detection of PVRIG expression in spleen by RT-PCR. 

Wild type: only one band at 291 bp with primers F1/R1(mPvrig); Homozygous: only one band at 351 bp with primers F2/R2(hPVRIG); Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hPVRIG expression in Daudi cells.

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Fig3. Detection of hPVRIG expression in Spleen in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

image.png

Fig4. Detection of hPVRIG expression in Blood in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

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