hCRLF2

모델명

C57BL/6JSmo-Crlf2tm1(hCRLF2)Smoc

카탈로그

NM-HU-210028

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol
Crlf2

Synonyms

CRLM2; Ly114; Tpte2; Tslpr

NCBI ID

57914

MGI ID

1889506

Ensembl ID

ENSMUSG00000033467

Pubmed

Crlf2

Human Ortholog

CRLF2

모델 설명

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.
신청분야：inmmue therapy；drug screening

검증 데이터

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Fig.1 Detection of hCRLF2 expression in the bone marrow of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

image.png

Fig.2 Detection of hCRLF2 expression in the blood of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

image.png

Fig.3 Detection of hCRLF2 expression in the spleen of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

image.png

Fig.4 Detection of mCRLF2 expression in the bone marrow of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

image.png

Fig.5 Detection of mCRLF2 expression in the blood of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

image.png

Fig.6 Detection of mCRLF2 expression in the spleen of hCRLF2 knockin mice. (male, 13-week-old)

Abbr.  WT, wild type; HO, homozygous.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

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