2210010C04Rik-D23A

모델명

C57BL/6Smoc-2210010C04Rikem1D23ASmoc

카탈로그

NM-KI-232248

모델 상태

Sperm cryopreservation

PDF 받기

모델 설명

These strains carry a D23A mutation of 2210010C04Rik gene.

검증 데이터

image.png

Fig 1. The pancreas of a heterozygous female mouse with RikD23A/+ mutation. 

Pancreatic tissue from 2-week-old and 23-week-old RikD23A/+ heterozygous female mice exhibited a loss of acinar cells, accompanied by infiltration of inflammatory cells, acinar-ductal metaplasia, fat infiltration, and fibrotic changes.The scale bar corresponds to 200 µm.


image.png

Pathology scores:0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked

图片1.png

Fig 2. The pancreas of a heterozygous male mouse with RikD23A/+ mutation

Pancreatic tissue from 4-week-old and 8-week-old RikD23A/+ heterozygous male mice exhibited a loss of acinar cells, accompanied by infiltration of inflammatory cells, acinar-ductal metaplasia, fat infiltration, and fibrotic changes;The degree of fat infiltration and fibrosis is not significant in 2-week-old mice, and other phenotypes are mild.The scale bar corresponds to 200 µm.

image.png

Pathology scores:0 represents within the normal range, 1 represents mild, 2 represents moderate, and 3 represents marked



당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회