고급 검색에 오신 것을 환영합니다

Models

About 42,575 results
마우스

Plp1-Flox

모델명：C57BL/6Smoc-Plp1em1(flox)Smoc
모델 상태：Embryo cryopreservation | 카탈로그：NM-CKO-200072
검증 데이터：无

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

마우스

NMG

모델명：NOD.Cg-PrkdcscidIl2rgem1Smoc
모델 상태：Repository Live | 카탈로그：NM-NSG-001
검증 데이터：有

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

마우스

hPD-1

모델명：C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00015
검증 데이터：有

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

마우스

CAG-hACE2-IRES-Luc-Tg

모델명：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
모델 상태：Repository Live | 카탈로그：NM-TG-200002
검증 데이터：有

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

마우스

hPD-L1

모델명：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-00062
검증 데이터：有

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

마우스

Alb-CreERT2

모델명：B6.129S-Albtm1.1(CreERT2)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-00002
검증 데이터：有

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.

마우스

R26-CAG-LSL-RSR-tdTomato-2A-DTR

모델명：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190086
검증 데이터：有

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

마우스

Kras-LSL-G12D

모델명：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
모델 상태：Repository Live | 카탈로그：NM-KI-190003
검증 데이터：有

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

마우스

hACE2

모델명：C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
모델 상태：Repository Live | 카탈로그：NM-HU-200218
검증 데이터：有

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

마우스

Ccr2-2A-DreERT2

모델명：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
모델 상태：Sperm cryopreservation | 카탈로그：NM-KI-200023
검증 데이터：有

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

위로