Ins2-C96Y

모델명

C57BL/6Smoc-Ins2em3(C96Y)Smoc

카탈로그

NM-KI-190096

모델 상태

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유전자 요약

Official Symbol
Ins2

Synonyms

Mody; Ins-2; InsII; Mody4; AA986540

NCBI ID

16334

MGI ID

96573

Ensembl ID

ENSMUSG00000000215

Pubmed

Ins2

Human Ortholog

INS2

모델 설명

These mice carry a p.C96Y mutation of Ins2 gene.
신청분야：Diabetes related.

Disease Connection

Diabetes

Phenotype(s)

MGI:3583904

Reference(s)

Yoshioka M, et al., A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice. Diabetes. 1997 May;46(5):887-94

검증 데이터

fig8.jpg

Fig.1 The Basic Symptoms of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.2 Body Weight of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.3 Blood Glucose Level of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

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Fig.4 Water Intake of Ins2-(C96Y) Mouse Comparedwith Its WT Litter Mate

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Fig.5 Food Intake of Ins2-(C96Y) Mouse Compared with Its WT Litter Mate

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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