Lep-KO
모델명
B6;129S-Leptm1Smoc
카탈로그
NM-KO-00034
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Lep
모델 설명
Disease Connection
검증 데이터
Fig1. Body weight and Blood glucose monitoring of ob/ob mice.
Fig2. Evaluation of Oral glucose tolerance test (OGTT) of female ob/ob mice.
Abbr. HO, homozygous; WT, wild type. **, P ≤ 0.01.
Note. The tested ob/ob and C57BL/6 mice were 6 weeks old.
Fig3. Detection of insulin levels in serum by ELISA.
Abbr. Hom, homozygous; HE, heterozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old.
Fig4. H&E staining of the subcutaneous adipose tissue (SAT) in ob/ob mice.
Abbr. HO, homozygous; WT, wild type; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 20.
Fig5. Representative pictures of pancreas in ob/ob mice.
These results suggested the inflammatory cell infiltration of the pancreas in ob/ob mice.
Abbr. HO, homozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 10.
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
조회