Il1b-Luc-Tg

모델명

B6.Cg-Tg(IL1B-luc)Smoc

카탈로그

NM-TG-00001

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol

Synonyms

Il-1b， IL-1beta

NCBI ID

16176

MGI ID

96543

Ensembl ID

ENSMUSG00000027398

Pubmed

Human Ortholog

IL1B

모델 설명

The transgenic mice model could be used to study transcriptional regulation of the IL-1βgene expression in the inflammatory process and evaluation the effect of anti-inflammatory drug in vivo.
신청분야：anti-inflammatory,inflammatory process

검증 데이터

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Fig.1 Time course of mean fluorescence intensity on the ventral and dorsal of Il1b-Luc-Tg mice after 5mg/mL LPS administration.

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Fig.2 Individual fluorescence intensity on the ventral (A) and dorsal (B) of Il1b-Luc-Tg mice treated with LPS.

간행물

Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice
References：BMC Immunol

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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