Snrpn-KO

모델명

C57BL/6Smoc-Snrpnem1Smoc

카탈로그

NM-KO-200644

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Snrpn

Synonyms

SMN， Peg4， sm-D， HCERN3， snRNP-N， 2410045I01Rik

NCBI ID

20646

MGI ID

98347

Ensembl ID

ENSMUSG00000102252

Pubmed

Snrpn

Human Ortholog

SNRPN

모델 설명

Exon 6 of Snrpn gene was deleted to generate Snrpn knockout mice.
신청분야：Related research on gene expression and main pathways of mRNA splicing

Disease Connection

Prader-Willi Syndrome

Phenotype(s)

MGI:3618139

Reference(s)

Yang T, Adamson TE, Resnick JL, Leff S, Wevrick R, Francke U , Jenkins NA , Copeland NG , Brannan CI, A mouse model for Prader-Willi syndrome imprinting-centre mutations. Nat Genet. 1998 May;19(1):25-31

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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