R26-CAG-LSL-Kras*G12C-IRES-Luc
모델명
C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-FRT-LSL-Kras(G12C)-IRES-Luciferase-polyA)Smoc
카탈로그
NM-KI-200323
모델 상태
Repository Live
유전자 요약
Official Symbol
Gt(ROSA)26Sor
모델 설명
검증 데이터
Fig1. The lung histological images were observed under microscope after H&E staining (Black arrows indicated representativetumor).
Lung: Focal inflammatory cell infiltration, Florid proliferation of tubular and glandular structures,infiltrating growth of lung Adenocarcinoma. Left: left lobe; RU: right upper lobe; RM: right middle lobe; RL: right lower Lobe; AL: accessory leaf.
Fig2. The expression of luciferase in R26-CAG-LSL-Kras*G12C-IRES-Luc mice was detected by in vivo imaging. The expression of luciferase in mice was observed on days 0, 26 and 31 by nasal drops infected with AAV-Cre virus.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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