Prokr2-2A-Dre

모델명

C57BL/6Smoc-Prokr2em1(2A-Dre)Smoc

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NM-KI-231591

모델 상태

Sperm cryopreservation

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Prokr2

모델 설명

The 2A-Dre expression cassette was knocked into the Prokr2 gene stop codon site.


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Fig1. Dre mediated recombination in brain of Prokr2DreERT2/+;Rosa26tdTomato/+ mouse.  3V:  third ventricle; SCN: suprachiasmatic nucleus

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Fig2. Detection of tdTomato(red) in various tissues of Prokr2DreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: brain, liver, kidney, spleen, testis, and adrenal gland. A few cells expressed in lungs, muscles, skin, pituitary gland. Tissues that unexpressed include spinal cord, retina, heart, stomach, salivary gland, brown fat, pancreas, small intestine, colon.(12-weeks old, male) (For more detailed information please contact our technical advisor.) 


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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