hFCRN/hALB(SD)
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SD-Fcgrtem1(hFCGRT)Albem3(hALB)Smoc
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NR-HU-233317
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Fig1. Detection of ALB expression in serum by blood biochemical analysis (n=4).
Abbr. HO, homozygous; WT, wild type.
Fig2. Detection of hALB and rat ALB expression in plasma by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig3. Expression characterization of hFCRN in hALB/hFCRN dKI rat by Western blot. (Arrow indicates expected molecular weight and asterisk indicates a nonspecific band)
Fig4. Blood concentration curve of test articles in hFcRn/hALB dKI rats.
In hFcRn/hALB dKI rats, the half-life time: TA-N434A > TA-YTE > TA. (In cooperation with the third party)
Fig5. PK study of Keytruda in hFCRN rat.
Fig6. PK study of Cyramza in hFCRN rat.
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