hCALCRL

모델명

C57BL/6Smoc-Calcrlem1(hCALCRL)Smoc

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NM-HU-225031

모델 상태

Embryo cryopreservation

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유전자 요약

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Calcrl

모델 설명

The endogenous mouse Calcrl gene was replaced by human CALCRL gene.

검증 데이터

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Fig1. Detection of CALCRL expression in lung by RT-PCR. Wild type: only one band at 281 bp with primers F1/R1 (mCalcrl); Homozygous: only one band at 163 bp with primers F2/R2 (hCALCRL). Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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Fig2. Detection of hCALCRL expression in Lung in C57BL/6 and HO hCALCRL knockin mice by IHC. Abbr. HO, homozygous; WT, wild type. Note. The anti-human CALCRL Antibody cross-reacted with mouse CALCRL and humanized CALCRL.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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