hVEGFA

모델명

C57BL/6Smoc-Vegfatm1(hVEGFA)/Smoc

카탈로그

NM-HU-2000028

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Vegfa

Synonyms

Vpf; Vegf

NCBI ID

22339

MGI ID

103178

Ensembl ID

ENSMUSG00000023951

Pubmed

Vegfa

Human Ortholog

VEGFA

모델 설명

The endogenous mouse Vegfa gene was replaced by human VEGFA gene. While hVEGFA(2)(Stock No.NM-HU-204984) mice function similarly to hVEGFA mice,for more detailed information please contact our technical advisor.
신청분야：Immunotherapy,drug screening

검증 데이터

image.png

Fig1. Detection of VEGFA expression in lung by RT-PCR. 

Wild type: only one band at 251 bp with primers F1/R1(mVegfa); Homozygous: only one band at 282 bp with primers F2/R2(hVEGFA);  

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hVEGFA expression in lung homogenate by ELISA. 

Note. The human VEGFA ELISA kit cross-reacted with mVEGFA and humanized VEGFA.

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회