hTSLP

모델명

C57BL/6Smoc-Tslptm2(hTSLP)/Smoc

카탈로그

NM-HU-2000064

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
TSLP

Synonyms

NCBI ID

53603

MGI ID

1855696

Ensembl ID

ENSMUSG00000024379

Pubmed

TSLP

Human Ortholog

TSLP

모델 설명

The endogenous mouse Tslp gene was replaced by human TSLP gene.
신청분야：Asthma research；drug screening

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image.png

Fig.1 Detection of TSLP expression in bladder by RT-PCR. 

Wild type: only one band at 168 bp with primers F1/R1 (mTslp);

Homozygous: only one band at 160 bp with primers F2/R2 (hTSLP); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hTSLP and mTSLP expression in thymus homogenate by ELISA (n=5). 

Abbr. HO, homozygous; WT, wild type.

Note. hTSLP and C57BL/6 mice were i.p. injected with LPS.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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