hTREM2

모델명

C57BL/6Smoc-Trem2em4(hTRem2)/Smoc

카탈로그

NM-HU-2000083

모델 상태

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Trem2

모델 설명

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.
신청분야:Alzheimer's disease research;drug screening

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Fig1. Detection of TREM2 expression in brain by RT-PCR. Wild type: only one band at 344 bp with primers F1/R1(mTrem2);Homoygous: only one band at 308 bp with primers F2/R2(hTREM2); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. hTREM2 Expression in Tumor-infiltrating Macrophages in hTREM2 Mice Bearing MC38 Syngenic Tumors. (Anti-hTREM2 antibody provided by the third party)

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Fig3. hTREM2 Expression in Tumor-infiltrating Macrophages in hTREM2 Mice Bearing MC38 Syngenic Tumors. (The commercial Anti-hTREM2 antibody has cross reactivity with mouse TREM2)


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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