hCD20(2)

모델명

C57BL/6Smoc-Ms4a1tm2 (hCD20)Smoc

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NM-HU-200114

모델 상태

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유전자 요약

Official Symbol
Ms4a1

Synonyms

Cd20; Ly-44; Ms4a2; AA960661

NCBI ID

12482

MGI ID

88321

Ensembl ID

ENSMUSG00000024673

Pubmed

Ms4a1

Human Ortholog

MS4A1

모델 설명

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.
신청분야：Immune-related; drug screening

검증 데이터

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Fig1. Detection of hCD20 expression on mCD19+ B cells in blood in hCD20 knockin mice.

NM-HU-200114-fig2.png

Fig2. Rituximab can bind to lymphocytes of hCD20 knockin mice.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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