hBCMA

모델명

C57BL/6Smoc-Tnfrsf17em1(hBCMA)Smoc

카탈로그

NM-HU-200228

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Tnfrsf17

모델 설명

The endogenous mice Bcma gene was replaced by human BCMA gene.

검증 데이터

image.png

Fig1. Detection of BCMA expression in large Intestine by RT-PCR. 

Wild type: only one band at 137 bp with primers F1/R1(mBcma);

Homozygous: only one band at 235 bp with primers F2/R2(hBCMA); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Expression characterization of hBCMA in spleen, small intestine and large intestine in homozygous hBCMA mice by western blot. 

Note: The anti-human BCMA antibody cross-reacted with mouse BCMA.


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

조회