hALB/hFCRN

모델명

C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc

카탈로그

NM-HU-200278

모델 상태

Repository Live

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유전자 요약

Official Symbol
FCGRT

Synonyms

FcRn

NCBI ID

14132

MGI ID

103017

Ensembl ID

ENSMUSG00000003420

Pubmed

FCGRT

Human Ortholog

FCGRT

Official Symbol
ALB

Synonyms

Alb1; Alb-1; BCL002

NCBI ID

11657

MGI ID

87991

Ensembl ID

ENSMUSG00000029368

Pubmed

ALB

Human Ortholog

ALB

Official Symbol
Fcgrt

Synonyms

FcRn

NCBI ID

14132

MGI ID

103017

Ensembl ID

ENSMUSG00000003420

Pubmed

Fcgrt

Human Ortholog

FCGRT

모델 설명

hALB(NM-HU-200003)was crossed with hFcRn(NM-HU-190070)to generate hALB/hFCRN mice

검증 데이터

image.png

Fig1. Detection of hALB and mALB expression in plasma by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig2. Expression characterization of hFCRN in hALB/hFCRN dKI mice by Western blot. 

Abbr. HO, homozygous; WT, wild type.

image.png


Fig3. In vivo PK profiles of TAA scfv-anti HSA VHH in hALB/hFCRN mice (In cooperation with the third party).

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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