hCCL4

모델명

C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc

카탈로그

NM-HU-210013

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Ccl4

Synonyms

Act-2; Mip1b; Scya4; MIP-1B; AT744.1

NCBI ID

20303

MGI ID

98261

Ensembl ID

ENSMUSG00000018930

Pubmed

Ccl4

Human Ortholog

CCL4

모델 설명

The endogenous mice Ccl4 gene was replaced by human CCL4 gene
신청분야：drug screening

검증 데이터

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Fig1. Detection of CCL4 expression in small intestine, spleen and  thymus by RT-PCR. Wild type: only one band at 242 bp with primers F1/R1(mCcl4); Homozygous: only one band at 144 bp with primers F2/R2(hCCL4); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig 2. Detection of hCCL4 expression in plasma by ELISA. Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hCCL4 and C57BL/6 mice were i.p. injected with LPS(20mg/kg) for 6h.

당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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