Abcb4-KO(FVB)
모델명
FVB-Abcb4em1Smoc
카탈로그
NM-KO-200584
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Abcb4
모델 설명
Exon 3-4 of Abcb4 gene was deleted to generate Abcb4 knockout mice.
Disease Connection
검증 데이터
Fig1. Serum biochemistry of Abcb4-KO mice (n=3 female and 3 male).
Fig2. Significant bile duct hyperplasia and interstitial focal cell infiltration were observed in the liver of Abcb4-KO mice.
(A) Liver were collected from FVB wild-type (+/+) and Abcb4-KO mice, and analyzed by HE staining. (B) Pathological analysis of the liver in Abcb4-KO mice.
Fig3. Collagen fiber hyperplasia were observed in the liver of Abcb4-KO mice.
(A) Liver were collected from FVB wild-type (+/+) and Abcb4-KO mice, and analyzed by Masson staining. (B) Quantification of the Collagen volume fraction (CVF) .
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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