R26-CAG-Loxp-tdTomato-Loxp-EGFP(SD)

모델명

SD-Gt(ROSA)26Sorem1(CAG-Loxp-tdTomato-3xpolyA-Loxp-EGFP)Smoc

카탈로그

NR-KI-190007

모델 상태

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유전자 요약

모델 설명

These rats harbor a CAG-Loxp-tdTomato-3xpolyA-Loxp-EGFP cassette in the Rosa26 locus generated by homologous recombination.
신청분야：Cre reporter

검증 데이터

tdTomato-EGFP-1.png

tdTomato-EGFP-2.png

Fig1. Validation of tdTomato expression by fluorescence assay.

The main organs Heart,  Liver, Spleen, Lung, Kidney, Brain & Thymus of R26-tdTomato +/- Rat were detected by fluorescence.

tdTomato-EGFP-3.png

tdTomato-EGFP-4.png

tdTomato-EGFP-5.png

Fig2. Confocal images showing expression of tdTomato in Heart, Liver, Spleen, Lung, Kidney, Brain & Thymus of R26- tdTomato +/- Rat. 

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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