R26-CAG-LSL-mCherry-EGFP-LC3
모델명
C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-mCherry-EGFP-Map1lc3a-pA)Smoc
카탈로그
NM-KI-00124
모델 상태
Repository Live
유전자 요약
Official Symbol
Gt(ROSA)26Sor
모델 설명
검증 데이터
Fig1. Detection of EGFP and RFP fluorescence intensity in brain, heart and liver tissues of R26-CAG-mCherry-EGFP-LC3 mice. Starvation(+): The mice were fasted for 48 hours; Starvation(-): The mice were fed normally.
Fig2. Detection of EGFP and RFP puncta in liver tissue sections of R26-CAG-mCherry-EGFP-LC3 mice. Starvation for 48 h increased the ratio of RFP/EGFP fluorescence expression in liver tissue of R26-CAG-mCherry-EGFP-LC3 mice. These results suggested there was increased fusion of autophagosomes with lysosomes after 48h starvation. Starvation(+): The mice were fasted for 48 hours; Starvation(-): The mice were fed normally.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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