H11-CAG-LSL-mtagBFP2

모델명

C57BL/6Smoc-lgs2em1(CAG-LSL-mTagBFP2)Smoc

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NM-KI-190006

모델 상태

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유전자 요약

Official Symbol

Synonyms

H11，Hipp11，Iis2

NCBI ID

Null

MGI ID

5461148

Ensembl ID

Null

Pubmed

모델 설명

A CAG-LSL-mTagBFP2-3xFLAG-WPRE-polyA cassette was inserted at the mouse H11 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the mTagBFP2-3xFLAG protein.
신청분야：Fluorescent reporter Mice

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Fig1. BFP expression in CAG-mTagBFP2/+ mouse, visualized using fluorescence imaging.

CAG-mTagBFP2/+ mouse was achieved through crossing CAG-LSL-mTagBFP2/+ mouse and Cre-expressing mouse. BFP expression in different organs of CAG-mTagBFP2/+ mouse was detected using fluorescence imaging, which suggests relatively high expression of BFP in a variety of organs. A: Images of different organs of CAG-mTagBFP2/+ mouse; B: Images of histologic sections of CAG-mTagBFP2/+ mouse under confocal microscopy.

 


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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