MC38-B2m KO

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Strain Information

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Fig1. Detection of B2M expression on in vitro cultured cells of MC38-B2M-KO cell line by FACS. 

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Fig2. Detection of B2M expression on in vitro cultured cells of MC38-B2M-KO cell line by WB. 

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Fig3. In vivo validation of MC38-B2M-KO cells in C57BL/6 mice (n=6).

C57BL/6 mice were inoculated with MC38-B2M-KO subcutaneously at 1×106 cells/mouse inoculum for tumor development.

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Fig4. B2M expression in tumors after in vivo growth of MC38-B2M-KO in wild type C57BL/6 mice

The tumors were collected at day 18 post tumor cell inoculation.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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